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(±)-Methyl Jasmonate

(±)-Methyl Jasmonate
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Purity:99.39%
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(±)-Methyl Jasmonate

Catalog No. T4900Cas No. 39924-52-2
Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester)induces the synthesis of proteinase inhibitors in plant leaves. In cancer cells, it suppresses proliferation and induces apoptosis. More specifically, methyl jasmonate inhibits hexokinase that is bound to mitochondria. As hexokinase is overexpressed in cancer cells and contributes to cancer cell growth and survival, methyl jasmonate's disruption of mitochondrial hexokinase activity selectively targets, and kills, cancer cells. Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate derivatives also have potential as anti-inflammatory agents. Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate has been primarily detected in urine.
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500 mg$41In Stock
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Product Introduction

Bioactivity
Description
Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester)induces the synthesis of proteinase inhibitors in plant leaves. In cancer cells, it suppresses proliferation and induces apoptosis. More specifically, methyl jasmonate inhibits hexokinase that is bound to mitochondria. As hexokinase is overexpressed in cancer cells and contributes to cancer cell growth and survival, methyl jasmonate's disruption of mitochondrial hexokinase activity selectively targets, and kills, cancer cells. Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate derivatives also have potential as anti-inflammatory agents. Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate has been primarily detected in urine.
Alias(±)-Jasmonic Acid methyl ester, Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate
Chemical Properties
Molecular Weight224.3
FormulaC13H20O3
Cas No.39924-52-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: Insoluble
DMSO: 55 mg/mL (245.21 mM)
Ethanol: 30 mg/mL
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4583 mL22.2916 mL44.5831 mL222.9157 mL
5 mM0.8917 mL4.4583 mL8.9166 mL44.5831 mL
10 mM0.4458 mL2.2292 mL4.4583 mL22.2916 mL
20 mM0.2229 mL1.1146 mL2.2292 mL11.1458 mL
50 mM0.0892 mL0.4458 mL0.8917 mL4.4583 mL
100 mM0.0446 mL0.2229 mL0.4458 mL2.2292 mL

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